September 16, 2026
Complex Regional Pain Syndrome (CRPS) is a chronic, often severe pain condition that typically affects a single limb following an injury, surgery, infection, or trauma. Unlike standard surgical or traumatic recovery, CRPS involves a malfunction of the autonomic—specifically sympathetic—nervous system, causing the brain to receive exaggerated, continuous pain signals.
When conservative measures fail to calm this overactive reflex, sympathetic nerve blocks provide a targeted interventional procedure designed to reset the sympathetic nervous system and relieve debilitating pain.
The sympathetic nervous system controls involuntary bodily functions, including blood vessel constriction, sweating, and body temperature regulation. In CRPS, these nerve pathways become abnormally hyperactive.
This dysfunction causes a characteristic triad of symptoms:
A sympathetic nerve block is an image-guided procedure in which a local anesthetic is injected directly around the sympathetic nerve ganglion supplying the affected limb.
Guided by real-time fluoroscopy (X-ray), an interventional specialist places a micro-needle adjacent to the nerve bundle and deposits an anesthetic solution. This temporarily turns off the sympathetic pain signals, allowing blood vessels to dilate and restoring normal temperature and micro-circulation to the limb.
Sympathetic nerve blocks serve two main purposes: