Understanding Central Sensitization: Why Some Pain Won’t Go Away

    November, 2025

    When pain lingers long after an injury has healed—or appears without a clear cause—it can feel confusing and frustrating. For many patients, this ongoing discomfort is linked to a condition called central sensitization, a complex process within the nervous system that turns the volume up on pain signals.

    At IGEA Brain, Spine, Pain and Orthopedics, we understand how debilitating chronic pain can be. Our team is committed to identifying the underlying causes and providing personalized, evidence-based treatments to help you reclaim your quality of life.

    What Is Central Sensitization

    Central sensitization occurs when the central nervous system (CNS)—which includes the brain and spinal cord—becomes overly responsive to pain signals. In this state, the body continues to interpret normal sensations, such as touch or movement, as painful, even after the original injury or condition has resolved. Essentially, the nervous system becomes “stuck” in a heightened state of sensitivity.

    Why It Happens

    Central sensitization can develop after an injury, surgery, or period of chronic inflammation. When the nervous system is exposed to continuous pain signals, it can undergo changes that make it more reactive over time. This is often seen in conditions such as fibromyalgia, chronic back pain, migraine, or certain post-surgical pain syndromes.

    Other factors—such as stress, poor sleep, and certain genetic predispositions—can also influence how the nervous system processes pain and contribute to the persistence of symptoms.

    How It Feels

    People experiencing central sensitization often describe their pain as widespread, persistent, or unpredictable. You might notice that everyday activities, light touch, or mild pressure trigger discomfort that feels disproportionate to the cause. Fatigue, brain fog, and sleep disturbances are also common, as chronic pain can take a toll on both body and mind.

    Finding Relief

    Although central sensitization can make pain feel overwhelming, it is treatable. The key lies in accurately diagnosing the condition and developing a plan that addresses both the physical and neurological components of pain.

    At IGEA Brain, Spine, Pain and Orthopedics, our specialists take a comprehensive, patient-focused approach. We evaluate your history, symptoms, and imaging to design an individualized care plan that targets the source of your pain and helps retrain your nervous system’s response. Our goal is to restore function, reduce discomfort, and help you return to the activities you love.

    Take the Next Step

    If your pain hasn’t improved with standard treatments—or if you’re tired of living with unexplained, persistent discomfort—it’s time to get answers. The pain specialists at IGEA Brain, Spine, Pain and Orthopedics are here to help you understand what’s happening and guide you toward lasting relief.

    Don’t wait another day to take control of your pain. Schedule your appointment with IGEA Brain, Spine, Pain and Orthopedics today.